ea0040oc4 | (1) | ESEBEC2016
Vinagre Joao
, Nabais Joana
, Pinheiro Jorge
, Batista Rui
, Oliveira Rui
, Goncalves Pedro
, Pestana Ana
, Reis Marta
, Mesquita Barbara
, Pinto Vasco
, Lyra Joana
, Godinho Miguel
, Lopes Jose Manuel
, Sobrinho-Simoes Manuel
, Soares Paula
Objective: One of the hallmarks of cancer is its unlimited replicative potential. Recently, telomerase promoter (TERTp) mutations were presented as novel mechanism for telomerase re-activation/expression. Due to this fact, it was our objective to study pancreatic endocrine tumours (PET) and related cell lines, to determine if TERTp mutations were present.Design: We performed characterization of the TERTp in a series of 55 PETs and three common PET cell l...